Rational antibiotic use

antibiotic prescribing review: rational or irrational therapy?

Rational Design of Antibiotic Treatment Plans

The development of reliable methods for restoring susceptibility after antibiotic resistance arises has proven elusive. A greater understanding of the relationship between antibiotic administration and the evolution of resistance is key to overcoming this challenge. Here we present a data-driven mathematical approach for developing antibiotic treatment plans that can reverse the evolution of an...

Access and Rational use of Plasma Protein Therapies (PPTs)

Antibiotic use

Is an antibiotic needed? Many diseases are not a result of bacterial infection and, especially when not severe, do not need antibiotics to manage them. Relevant examples include mild calf scours and outbreaks of coughing without other signs among growing cattle. Even in more severe cases of scour and pneumonia, the effect of antibiotics may be to protect the animal from secondary infection rath...

The Rational Use of Antibiotics and in Relation to Antibiotic Resistance

When antimicrobials are used there is always a risk that the selection of antimicrobial resistance will occur. Some bacterial species appear to develop resistance more quickly than others, such as Escherichia coli and some antimicrobials have resistance developed quite easily against them e.g. the tetracyclines. The first approach is to avoid or reduce the use of antimicrobials by using high he...